Anti-Gliadin Antibodies in Dermatitis Herpetiformis
نویسندگان
چکیده
منابع مشابه
Antigliadin antibodies in dermatitis herpetiformis.
DERMATITIS herpetiformis (DH) is an intensely itchy dermatosis of a chronic nature. Although the lesions most often consist of tense vesicles grouped on the extensor surfaces of the body, they may also be erythematous, urticarial or papular and more diffuse. As a result of the intense itch the lesions are excoriated and frequently present as small crusted areas. Thus other parameters are necess...
متن کاملAssociation between Levels of IgA Antibodies to Tissue Transglutaminase and Gliadin-Related Nonapeptides in Dermatitis Herpetiformis
Dermatitis herpetiformis (DH) is an autoimmunity-driven inflammatory blistering dermatosis associated with a gluten-dependent enteropathy. Tissue transglutaminase (tTG) and nonapeptides of gliadin (npG) are considered in its pathomechanism/diagnostics. Here, the diagnostic accuracy of anti-tTG/anti-npG IgA ELISAs in Slavic DH patients with active skin rash was assessed through creating receiver...
متن کاملDermatitis herpetiformis.
Dermatitis herpetiformis (DH) is an autoimmune, pleiomorphic, papulovesicular disorder associated with celiac disease and gluten sensitivity. DH is characterized by subepidermal bullae on hematoxylin and eosin staining and granular immunoglobulin A deposits in the dermal papillae using the direct immunofluorescence method. Antibodies to tissue transglutaminase and epidermal transgulatminase can...
متن کاملDermatitis herpetiformis.
Dermatitis herpetiformis (DH), described over 100 years ago, is a life-long blistering skin disease that can appear at any age. Dapsone controls the rash effectively and has been used for over 50 years in the treatment of DH. Major landmark in the research of DH was 30 years ago the discovery of granular IgA deposits in the upper papillary dermis,1 and further differentiation of an autoimmune d...
متن کاملDermatitis herpetiformis and vitiligo.
Dermatitis herpetiformis (DH) is a rare immunobullous disorder of the skin that is associated with gluten hypersensitivity. Subepidermal IgA-type antibody deposition against tissue transglutaminase leads to dense neutrophilic microabscess and eventually into vesicles in dermal papillae, which may occasionally merge into bullae. Being a subepidermal vesiculobullous disorder, DH is frequently ass...
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 1981
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107688107400614